Principal Data Scientist jobs in England

Lead/Principal Data Scientist London - 3 days a week Up to £135,000 About the Company We’re working with a next-generation private markets firm that is redefining value creation by combining deep industry expertise with data science and machine learning. This is a unique opportunity to join a company that partners directly with portfolio companies to drive measurable operational and financial...

This role is for a Principal/Senior Data Scientist on a 2‐year contract, offering an annual salary of £44,905‐£63,815. It is located in a hybrid work environment in Hinxton, England, United Kingdom. Candidates should have expertise in machine learning, Python, and experience in computational biology or related fields. About Us We are hiring a Senior Data Scientist/Principal Data Scientist to...

Posted Thursday 22 January 2026 at 01:00 | Expires Sunday 8 February 2026 at 00:59 At World of Books, we're on a mission to become the Planet's Bookstore — helping people read more while wasting less. As a certified B-Corp and a £200m+ global ecommerce business, data science sits at the heart of how we price millions of books sustainably and profitably. We're now looking for a Principal Data...

You will be working in a dynamic environment with a team that is motivated to deliver innovative solutions to customers within defence, government and commercial sectors. We are after creative, passionate, technically savvy and personable people to help grow our practice and solve some of the most challenging, exciting and critical challenges to the UK's digital landscape.

You will lead the ideation, research, modeling, and implementation of new AI-driven features — with a strong focus on Large Language Models (LLMs), Generative AI, and advanced Machine Learning.

You will also contribute to the company's long‐term AI strategy and act as a thought leader and role model within the data science teams.

You will help lead and set technical and strategic direction for the group, support customer and stakeholder engagement, and deliver technical solutions on internal and external projects.

You will shape the vision, set the technical direction, and drive strategic impact through innovative analytical solutions. This role is both highly technical and deeply collaborative, requiring excellence in leadership, communication, and cross-functional influence.

Head / Principal Data Scientist, Analytics & Machine Learning Join to apply for the Head / Principal Data Scientist, Analytics & Machine Learning role at Valink Therapeutics Salary: Competitive salary at Director or Principal level, depending on experience. Location: White City, London, UK Starting date: Jan-Feb 2026 Role Summary The Principal Data Scientist will help shape and execute our...

A leading AI consultancy in Greater London is seeking a Principal Data Scientist to lead high-impact projects and mentor fellow data scientists. The ideal candidate will have extensive experience in machine learning and generative AI, advanced coding skills in Python, and a passion for mentoring. As a technical authority, you will contribute to project bidding processes and drive innovation...

A leading research organization in Cambridge is seeking a Senior Data Scientist/Principal Data Scientist to work on transformative projects involving single-cell genomics and generative AI. The role involves building next-generation models, collaborating with top research teams, and leading innovative AI-driven initiatives in health and biology. The ideal candidate will have a PhD and experience...

Bitsight is a cyber risk management leader transforming how companies manage exposure, performance, and risk for themselves and their third parties. Companies rely on Bitsight to prioritize their cybersecurity investments, build greater trust within their ecosystem, and reduce their chances of financial loss. Built on over a decade of technological innovation, its integrated solutions deliver...

You will help set the direction for AI and data science across the business, driving the adoption of modern AI development practices and scalable, cloud‐native architectures at enterprise scale.

You will provide technical and thought leadership, engaging with C‐level and senior stakeholders to define architectural principles and strategic direction.

Brief Description The Principal, AI Data Scientist will be responsible for supporting the implementation of innovative, complex and transformative AI/ML/GenAI solutions across the areas of Clinical Trial Execution and Digital Healthcare across Jazz Research and Development. Essential Functions - Support the development and implementation of AI/ML/GenAI solutions to optimize clinical trial...

At World of Books, we're on a mission to become the Planet's Bookstore — helping people read more while wasting less. As a certified B-Corp and a £200m+ global ecommerce business, data science sits at the heart of how we price millions of books sustainably and profitably. We're now looking for a Principal Data Scientist to play a critical technical leadership role in shaping how advanced...

You will help lead and set technical and strategic direction for the group, support with customer and stakeholder engagement and deliver technical solutions on internal and external projects. Skills and Experience

A prominent health organization is seeking a Senior Principal Data Scientist in London to lead data science initiatives in clinical development. This role requires extensive experience in data science and AI, with a focus on neuroscience and clinical trials. The ideal candidate will have a Ph.D. and strong programming skills in R and Python. This position offers a hybrid work model, fostering a...

You will enjoy a strong compensation package, comprehensive benefits, and ongoing investment in career growth and skill development. Industry leadership**: This is an opportunity to be a founding member of the organization that's delivering brand-new products that democratize modeling and analytics solutions.

You will be part of a collaborative and creative culture where we encourage new ideas.

You will set the technical direction, drive innovation, and mentor teams to shape the company's data science strategy. This position focuses on deep individual contribution and technical excellence, influencing the broader data science community. What you'll be doing:

If you are a current Jazz employee please apply via the Internal Career site. Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases — often with limited or no therapeutic options. We have a diverse portfolio of marketed...

A leading UK AI and data solutions company is seeking a Principal Data Scientist to deliver sophisticated AI solutions. The successful candidate will direct AI practices, mentor teams, and engage with stakeholders to ensure ethical and effective deployment of AI technology, including extensive collaboration and leadership in innovative projects. This role provides opportunities for significant...