Principal Data Scientist jobs in England

Lead/Principal Data Scientist London - 3 days a week Up to £135,000 About the Company We’re working with a next-generation private markets firm that is redefining value creation by combining deep industry expertise with data science and machine learning. This is a unique opportunity to join a company that partners directly with portfolio companies to drive measurable operational and financial...

Lead/Principal Data Scientist London - 3 days a week Up to £135,000 About the Company We’re working with a next-generation private markets firm that is redefining value creation by combining deep industry expertise with data science and machine learning. This is a unique opportunity to join a company that partners directly with portfolio companies to drive measurable operational and financial...

You will collaborate closely with software engineers, data scientists, and domain experts to translate cutting‐edge research into operational, trading‐ready intelligence.

A leading AI and data solutions company in Greater London is seeking a Principal Data Scientist to drive impactful AI solutions using state-of-the-art technologies. The role involves leading a community of experts while engaging with C-level executives, ensuring the use of responsible AI practices. This is an opportunity to be part of an inclusive, diverse team committed to innovation and...

NBCUniversal is one of the world's leading media and entertainment companies. We create world-class content, which we distribute across our portfolio of film, television, and streaming, and bring to life through our theme parks and consumer experiences. We own and operate leading entertainment and news brands, including NBC, NBC News, MSNBC, CNBC, NBC Sports, Telemundo, NBC Local Stations, Bravo,...

You will contribute to (lead - principal data scientist) transformative projects that integrate single-cell genomics, spatial transcriptomics, and generative AI to build next-generation models for understanding tissue biology and cellular dynamics across organs such as the pancreas, kidney, skin, and liver.

At World of Books, we're on a mission to become the Planet's Bookstore — helping people read more while wasting less. As a certified B-Corp and a £200m+ global ecommerce business, data science sits at the heart of how we price millions of books sustainably and profitably. We're now looking for a Principal Data Scientist to play a critical technical leadership role in shaping how advanced...

A leading research organization in Cambridge is seeking a Senior Data Scientist/Principal Data Scientist to work on transformative projects involving single-cell genomics and generative AI. The role involves building next-generation models, collaborating with top research teams, and leading innovative AI-driven initiatives in health and biology. The ideal candidate will have a PhD and experience...

Bitsight is a cyber risk management leader transforming how companies manage exposure, performance, and risk for themselves and their third parties. Companies rely on Bitsight to prioritize their cybersecurity investments, build greater trust within their ecosystem, and reduce their chances of financial loss. Built on over a decade of technological innovation, its integrated solutions deliver...

Brief Description The Principal, AI Data Scientist will be responsible for supporting the implementation of innovative, complex and transformative AI/ML/GenAI solutions across the areas of Clinical Trial Execution and Digital Healthcare across Jazz Research and Development. Essential Functions - Support the development and implementation of AI/ML/GenAI solutions to optimize clinical trial...

You will set the technical direction, drive innovation, and mentor teams to shape the company's data science strategy. This position focuses on deep individual contribution and technical excellence, influencing the broader data science community. What you'll be doing:

You will lead and contribute to transformative projects that integrate single-cell genomics, spatial transcriptomics, and generative AI to build next-generation models for understanding tissue biology and cellular dynamics across organs such as the pancreas, kidney, skin, and liver.

You will lead the ideation, research, modeling, and implementation of new AI-driven features — with a strong focus on Large Language Models (LLMs), Generative AI, and advanced Machine Learning.

You will also contribute to the company's long-term AI strategy and act as a thought leader and role model within the data science teams.

Summary - Responsibility: Plan and execute Valink's data strategy to build predictive models for drug discovery and drug positioning - Salary: Competitive salary at Director or Principal level, depending on experience - Starting date: Jan-Feb 2026 - Location: White City, London, UK About Us Valink Therapeutics is a spinout from the University of Oxford with a mission to revolutionise...

You will manage the delivery of impactful data science projects and mentor fellow data scientists. Your role is pivotal in enhancing underwriting capabilities and influencing the entire insurance value chain through advanced analytics and problem-solving techniques. Join a dynamic team and enjoy a supportive company culture with great employee benefits.

A leading technology firm in Greater London is seeking a Principal Data Scientist to design and implement advanced AI and ML methodologies. The ideal candidate will have a PhD in a quantitative field, proficiency in Python, and experience across the ML lifecycle. Responsibilities include collaborating with software engineers and translating complex research into actionable intelligence. The...

A leading biotechnology firm is seeking a Principal Data Scientist to shape and execute data strategies for drug discovery. This role involves building predictive models and integrating datasets to enhance drug candidate testing. Candidates should have a PhD or MSc, with over 5 years of relevant experience, machine learning expertise, and strong programming skills in Python and R. Flexible...

A global biopharma company in Greater London seeks a Principal, AI Data Scientist to implement innovative AI/ML solutions across Clinical Trial Execution and Digital Healthcare. Ideal candidates will possess strong programming skills in Python or R, experience with ML frameworks, and a background in healthcare data. This role offers competitive benefits including medical, dental, and flexible...

You will help set the direction for AI and data science across the business, driving the adoption of modern AI development practices and scalable, cloud‐native architectures at enterprise scale.

You will provide technical and thought leadership, engaging with C‐level and senior stakeholders to define architectural principles and strategic direction.

A leading UK AI and data solutions company is seeking a Principal Data Scientist to deliver sophisticated AI solutions. The successful candidate will direct AI practices, mentor teams, and engage with stakeholders to ensure ethical and effective deployment of AI technology, including extensive collaboration and leadership in innovative projects. This role provides opportunities for significant...